Review





Similar Products

il 22r  (R&D Systems)
91
R&D Systems il 22r
Il 22r, supplied by R&D Systems, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mouse+il-22+pe-conjugated+antibody/Mouse+IL-22+R+alpha+1+PE-conjugated+Antibody/pm31148320-104-4-5
Average 91 stars, based on 1 article reviews
il 22r - by Bioz Stars, 2026-10
91/100 stars
  Buy from Supplier
il22ra1  (R&D Systems)
91
R&D Systems il22ra1
<t>Il22ra1</t> is expressed heterogeneously throughout the crypt. ( A ) The Il22ra1 gene expression profile characterized in FACS-isolated total epithelium (CD326+), absorptive/goblet differentiated cells (Sox9-EGFP neg ), TA progenitor cells (Sox9-EGFP sublow ), ISCs (Sox9-EGFP low ), enteroendocrine/tuft cells (Sox9-EGFP high ), and Paneth cells (Sox9-EGFP high , CD24 high ). Technical replicate n = 3; biological N = 3 mice. Significance was calculated by 1-way analysis of variance with Tukey multiple comparisons; bars that are not connected by the same letter are statistically significant ( P < .05). ( B ) Left : t-SNE analysis of single-cell RNA sequence analysis of mouse small intestinal epithelium. Each color represents a different population defined in the original analysis based on lineage-specific transcriptomic signatures. Right : Table depicts the number of cells in each lineage category expressing IL22ra1. ( C ) Cells from the t-SNE profiles in the graph in panel B are highlighted specifically for the expression of IL22ra1 levels in all epithelial cells. Darker shades of grey represent higher expression levels. Pink circles represent no expression. ( D ) The same analysis in panel C except only ISCs are shown. ( E ) The same analysis in panel C except only TA progenitors are shown. ( F ) Representative immunohistochemistry of IL22RA1 (red) and cell nuclei (blue) in a mouse ileal crypt. ( G ) FACS analysis of fixed cell populations described in panel A stained for IL22RA1. Technical replicate n = 3; biological N = 3 mice. Bars represent parts of whole. EC, enterocyte; EE, enteroendocrine; EEC, enteroendocrine; Max, maximum; Min, minimum.
Il22ra1, supplied by R&D Systems, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mouse+il-22+pe-conjugated+antibody/Mouse+IL-22+R+alpha+1+PE-conjugated+Antibody/pmc06199238-290-36-40
Average 91 stars, based on 1 article reviews
il22ra1 - by Bioz Stars, 2026-10
91/100 stars
  Buy from Supplier
mouse anti-human pe-conjugated anti-il-22 antibody  (Thermo Fisher)
90
Thermo Fisher mouse anti-human pe-conjugated anti-il-22 antibody
<t>Il22ra1</t> is expressed heterogeneously throughout the crypt. ( A ) The Il22ra1 gene expression profile characterized in FACS-isolated total epithelium (CD326+), absorptive/goblet differentiated cells (Sox9-EGFP neg ), TA progenitor cells (Sox9-EGFP sublow ), ISCs (Sox9-EGFP low ), enteroendocrine/tuft cells (Sox9-EGFP high ), and Paneth cells (Sox9-EGFP high , CD24 high ). Technical replicate n = 3; biological N = 3 mice. Significance was calculated by 1-way analysis of variance with Tukey multiple comparisons; bars that are not connected by the same letter are statistically significant ( P < .05). ( B ) Left : t-SNE analysis of single-cell RNA sequence analysis of mouse small intestinal epithelium. Each color represents a different population defined in the original analysis based on lineage-specific transcriptomic signatures. Right : Table depicts the number of cells in each lineage category expressing IL22ra1. ( C ) Cells from the t-SNE profiles in the graph in panel B are highlighted specifically for the expression of IL22ra1 levels in all epithelial cells. Darker shades of grey represent higher expression levels. Pink circles represent no expression. ( D ) The same analysis in panel C except only ISCs are shown. ( E ) The same analysis in panel C except only TA progenitors are shown. ( F ) Representative immunohistochemistry of IL22RA1 (red) and cell nuclei (blue) in a mouse ileal crypt. ( G ) FACS analysis of fixed cell populations described in panel A stained for IL22RA1. Technical replicate n = 3; biological N = 3 mice. Bars represent parts of whole. EC, enterocyte; EE, enteroendocrine; EEC, enteroendocrine; Max, maximum; Min, minimum.
Mouse Anti Human Pe Conjugated Anti Il 22 Antibody, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mouse+il-22+pe-conjugated+antibody/pm27059796-51-25-27
Average 90 stars, based on 1 article reviews
mouse anti-human pe-conjugated anti-il-22 antibody - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier
mouse monoclonal anti human il 22r1 pe antibody  (R&D Systems)
93
R&D Systems mouse monoclonal anti human il 22r1 pe antibody
<t>Il22ra1</t> is expressed heterogeneously throughout the crypt. ( A ) The Il22ra1 gene expression profile characterized in FACS-isolated total epithelium (CD326+), absorptive/goblet differentiated cells (Sox9-EGFP neg ), TA progenitor cells (Sox9-EGFP sublow ), ISCs (Sox9-EGFP low ), enteroendocrine/tuft cells (Sox9-EGFP high ), and Paneth cells (Sox9-EGFP high , CD24 high ). Technical replicate n = 3; biological N = 3 mice. Significance was calculated by 1-way analysis of variance with Tukey multiple comparisons; bars that are not connected by the same letter are statistically significant ( P < .05). ( B ) Left : t-SNE analysis of single-cell RNA sequence analysis of mouse small intestinal epithelium. Each color represents a different population defined in the original analysis based on lineage-specific transcriptomic signatures. Right : Table depicts the number of cells in each lineage category expressing IL22ra1. ( C ) Cells from the t-SNE profiles in the graph in panel B are highlighted specifically for the expression of IL22ra1 levels in all epithelial cells. Darker shades of grey represent higher expression levels. Pink circles represent no expression. ( D ) The same analysis in panel C except only ISCs are shown. ( E ) The same analysis in panel C except only TA progenitors are shown. ( F ) Representative immunohistochemistry of IL22RA1 (red) and cell nuclei (blue) in a mouse ileal crypt. ( G ) FACS analysis of fixed cell populations described in panel A stained for IL22RA1. Technical replicate n = 3; biological N = 3 mice. Bars represent parts of whole. EC, enterocyte; EE, enteroendocrine; EEC, enteroendocrine; Max, maximum; Min, minimum.
Mouse Monoclonal Anti Human Il 22r1 Pe Antibody, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mouse+il-22+pe-conjugated+antibody/Human+IL-22+R+alpha+1+PE-conjugated+Antibody/pm27801948-67-19-26
Average 93 stars, based on 1 article reviews
mouse monoclonal anti human il 22r1 pe antibody - by Bioz Stars, 2026-10
93/100 stars
  Buy from Supplier
mouse anti human il 22 phycoerythrin pe  (R&D Systems)
91
R&D Systems mouse anti human il 22 phycoerythrin pe
<t>Il22ra1</t> is expressed heterogeneously throughout the crypt. ( A ) The Il22ra1 gene expression profile characterized in FACS-isolated total epithelium (CD326+), absorptive/goblet differentiated cells (Sox9-EGFP neg ), TA progenitor cells (Sox9-EGFP sublow ), ISCs (Sox9-EGFP low ), enteroendocrine/tuft cells (Sox9-EGFP high ), and Paneth cells (Sox9-EGFP high , CD24 high ). Technical replicate n = 3; biological N = 3 mice. Significance was calculated by 1-way analysis of variance with Tukey multiple comparisons; bars that are not connected by the same letter are statistically significant ( P < .05). ( B ) Left : t-SNE analysis of single-cell RNA sequence analysis of mouse small intestinal epithelium. Each color represents a different population defined in the original analysis based on lineage-specific transcriptomic signatures. Right : Table depicts the number of cells in each lineage category expressing IL22ra1. ( C ) Cells from the t-SNE profiles in the graph in panel B are highlighted specifically for the expression of IL22ra1 levels in all epithelial cells. Darker shades of grey represent higher expression levels. Pink circles represent no expression. ( D ) The same analysis in panel C except only ISCs are shown. ( E ) The same analysis in panel C except only TA progenitors are shown. ( F ) Representative immunohistochemistry of IL22RA1 (red) and cell nuclei (blue) in a mouse ileal crypt. ( G ) FACS analysis of fixed cell populations described in panel A stained for IL22RA1. Technical replicate n = 3; biological N = 3 mice. Bars represent parts of whole. EC, enterocyte; EE, enteroendocrine; EEC, enteroendocrine; Max, maximum; Min, minimum.
Mouse Anti Human Il 22 Phycoerythrin Pe, supplied by R&D Systems, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mouse+il-22+pe-conjugated+antibody/Human+IL-22+PE-conjugated+Antibody/pm24908311-54-0-4
Average 91 stars, based on 1 article reviews
mouse anti human il 22 phycoerythrin pe - by Bioz Stars, 2026-10
91/100 stars
  Buy from Supplier
il 22  (R&D Systems)
90
R&D Systems il 22
<t>Il22ra1</t> is expressed heterogeneously throughout the crypt. ( A ) The Il22ra1 gene expression profile characterized in FACS-isolated total epithelium (CD326+), absorptive/goblet differentiated cells (Sox9-EGFP neg ), TA progenitor cells (Sox9-EGFP sublow ), ISCs (Sox9-EGFP low ), enteroendocrine/tuft cells (Sox9-EGFP high ), and Paneth cells (Sox9-EGFP high , CD24 high ). Technical replicate n = 3; biological N = 3 mice. Significance was calculated by 1-way analysis of variance with Tukey multiple comparisons; bars that are not connected by the same letter are statistically significant ( P < .05). ( B ) Left : t-SNE analysis of single-cell RNA sequence analysis of mouse small intestinal epithelium. Each color represents a different population defined in the original analysis based on lineage-specific transcriptomic signatures. Right : Table depicts the number of cells in each lineage category expressing IL22ra1. ( C ) Cells from the t-SNE profiles in the graph in panel B are highlighted specifically for the expression of IL22ra1 levels in all epithelial cells. Darker shades of grey represent higher expression levels. Pink circles represent no expression. ( D ) The same analysis in panel C except only ISCs are shown. ( E ) The same analysis in panel C except only TA progenitors are shown. ( F ) Representative immunohistochemistry of IL22RA1 (red) and cell nuclei (blue) in a mouse ileal crypt. ( G ) FACS analysis of fixed cell populations described in panel A stained for IL22RA1. Technical replicate n = 3; biological N = 3 mice. Bars represent parts of whole. EC, enterocyte; EE, enteroendocrine; EEC, enteroendocrine; Max, maximum; Min, minimum.
Il 22, supplied by R&D Systems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mouse+il-22+pe-conjugated+antibody/Mouse+IL-22+PE-conjugated+Antibody/pm22854287-84-28-30
Average 90 stars, based on 1 article reviews
il 22 - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier
mouse pe conjugated mab anti human il 22  (R&D Systems)
91
R&D Systems mouse pe conjugated mab anti human il 22
<t>Il22ra1</t> is expressed heterogeneously throughout the crypt. ( A ) The Il22ra1 gene expression profile characterized in FACS-isolated total epithelium (CD326+), absorptive/goblet differentiated cells (Sox9-EGFP neg ), TA progenitor cells (Sox9-EGFP sublow ), ISCs (Sox9-EGFP low ), enteroendocrine/tuft cells (Sox9-EGFP high ), and Paneth cells (Sox9-EGFP high , CD24 high ). Technical replicate n = 3; biological N = 3 mice. Significance was calculated by 1-way analysis of variance with Tukey multiple comparisons; bars that are not connected by the same letter are statistically significant ( P < .05). ( B ) Left : t-SNE analysis of single-cell RNA sequence analysis of mouse small intestinal epithelium. Each color represents a different population defined in the original analysis based on lineage-specific transcriptomic signatures. Right : Table depicts the number of cells in each lineage category expressing IL22ra1. ( C ) Cells from the t-SNE profiles in the graph in panel B are highlighted specifically for the expression of IL22ra1 levels in all epithelial cells. Darker shades of grey represent higher expression levels. Pink circles represent no expression. ( D ) The same analysis in panel C except only ISCs are shown. ( E ) The same analysis in panel C except only TA progenitors are shown. ( F ) Representative immunohistochemistry of IL22RA1 (red) and cell nuclei (blue) in a mouse ileal crypt. ( G ) FACS analysis of fixed cell populations described in panel A stained for IL22RA1. Technical replicate n = 3; biological N = 3 mice. Bars represent parts of whole. EC, enterocyte; EE, enteroendocrine; EEC, enteroendocrine; Max, maximum; Min, minimum.
Mouse Pe Conjugated Mab Anti Human Il 22, supplied by R&D Systems, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mouse+il-22+pe-conjugated+antibody/Human+IL-22+PE-conjugated+Antibody/pm22237036-28-0-9
Average 91 stars, based on 1 article reviews
mouse pe conjugated mab anti human il 22 - by Bioz Stars, 2026-10
91/100 stars
  Buy from Supplier
unconjugated mouse anti human il 22ra1  (R&D Systems)
93
R&D Systems unconjugated mouse anti human il 22ra1
<t>Il22ra1</t> is expressed heterogeneously throughout the crypt. ( A ) The Il22ra1 gene expression profile characterized in FACS-isolated total epithelium (CD326+), absorptive/goblet differentiated cells (Sox9-EGFP neg ), TA progenitor cells (Sox9-EGFP sublow ), ISCs (Sox9-EGFP low ), enteroendocrine/tuft cells (Sox9-EGFP high ), and Paneth cells (Sox9-EGFP high , CD24 high ). Technical replicate n = 3; biological N = 3 mice. Significance was calculated by 1-way analysis of variance with Tukey multiple comparisons; bars that are not connected by the same letter are statistically significant ( P < .05). ( B ) Left : t-SNE analysis of single-cell RNA sequence analysis of mouse small intestinal epithelium. Each color represents a different population defined in the original analysis based on lineage-specific transcriptomic signatures. Right : Table depicts the number of cells in each lineage category expressing IL22ra1. ( C ) Cells from the t-SNE profiles in the graph in panel B are highlighted specifically for the expression of IL22ra1 levels in all epithelial cells. Darker shades of grey represent higher expression levels. Pink circles represent no expression. ( D ) The same analysis in panel C except only ISCs are shown. ( E ) The same analysis in panel C except only TA progenitors are shown. ( F ) Representative immunohistochemistry of IL22RA1 (red) and cell nuclei (blue) in a mouse ileal crypt. ( G ) FACS analysis of fixed cell populations described in panel A stained for IL22RA1. Technical replicate n = 3; biological N = 3 mice. Bars represent parts of whole. EC, enterocyte; EE, enteroendocrine; EEC, enteroendocrine; Max, maximum; Min, minimum.
Unconjugated Mouse Anti Human Il 22ra1, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mouse+il-22+pe-conjugated+antibody/Human+IL-22+R+alpha+1+PE-conjugated+Antibody/pmc03026902-102-17-24
Average 93 stars, based on 1 article reviews
unconjugated mouse anti human il 22ra1 - by Bioz Stars, 2026-10
93/100 stars
  Buy from Supplier
anti il 22 mab 140301  (R&D Systems)
90
R&D Systems anti il 22 mab 140301
<t>Il22ra1</t> is expressed heterogeneously throughout the crypt. ( A ) The Il22ra1 gene expression profile characterized in FACS-isolated total epithelium (CD326+), absorptive/goblet differentiated cells (Sox9-EGFP neg ), TA progenitor cells (Sox9-EGFP sublow ), ISCs (Sox9-EGFP low ), enteroendocrine/tuft cells (Sox9-EGFP high ), and Paneth cells (Sox9-EGFP high , CD24 high ). Technical replicate n = 3; biological N = 3 mice. Significance was calculated by 1-way analysis of variance with Tukey multiple comparisons; bars that are not connected by the same letter are statistically significant ( P < .05). ( B ) Left : t-SNE analysis of single-cell RNA sequence analysis of mouse small intestinal epithelium. Each color represents a different population defined in the original analysis based on lineage-specific transcriptomic signatures. Right : Table depicts the number of cells in each lineage category expressing IL22ra1. ( C ) Cells from the t-SNE profiles in the graph in panel B are highlighted specifically for the expression of IL22ra1 levels in all epithelial cells. Darker shades of grey represent higher expression levels. Pink circles represent no expression. ( D ) The same analysis in panel C except only ISCs are shown. ( E ) The same analysis in panel C except only TA progenitors are shown. ( F ) Representative immunohistochemistry of IL22RA1 (red) and cell nuclei (blue) in a mouse ileal crypt. ( G ) FACS analysis of fixed cell populations described in panel A stained for IL22RA1. Technical replicate n = 3; biological N = 3 mice. Bars represent parts of whole. EC, enterocyte; EE, enteroendocrine; EEC, enteroendocrine; Max, maximum; Min, minimum.
Anti Il 22 Mab 140301, supplied by R&D Systems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mouse+il-22+pe-conjugated+antibody/Mouse+IL-22+PE-conjugated+Antibody/pm19342625-51-1-7
Average 90 stars, based on 1 article reviews
anti il 22 mab 140301 - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier

Image Search Results


Il22ra1 is expressed heterogeneously throughout the crypt. ( A ) The Il22ra1 gene expression profile characterized in FACS-isolated total epithelium (CD326+), absorptive/goblet differentiated cells (Sox9-EGFP neg ), TA progenitor cells (Sox9-EGFP sublow ), ISCs (Sox9-EGFP low ), enteroendocrine/tuft cells (Sox9-EGFP high ), and Paneth cells (Sox9-EGFP high , CD24 high ). Technical replicate n = 3; biological N = 3 mice. Significance was calculated by 1-way analysis of variance with Tukey multiple comparisons; bars that are not connected by the same letter are statistically significant ( P < .05). ( B ) Left : t-SNE analysis of single-cell RNA sequence analysis of mouse small intestinal epithelium. Each color represents a different population defined in the original analysis based on lineage-specific transcriptomic signatures. Right : Table depicts the number of cells in each lineage category expressing IL22ra1. ( C ) Cells from the t-SNE profiles in the graph in panel B are highlighted specifically for the expression of IL22ra1 levels in all epithelial cells. Darker shades of grey represent higher expression levels. Pink circles represent no expression. ( D ) The same analysis in panel C except only ISCs are shown. ( E ) The same analysis in panel C except only TA progenitors are shown. ( F ) Representative immunohistochemistry of IL22RA1 (red) and cell nuclei (blue) in a mouse ileal crypt. ( G ) FACS analysis of fixed cell populations described in panel A stained for IL22RA1. Technical replicate n = 3; biological N = 3 mice. Bars represent parts of whole. EC, enterocyte; EE, enteroendocrine; EEC, enteroendocrine; Max, maximum; Min, minimum.

Journal: Cellular and Molecular Gastroenterology and Hepatology

Article Title: IL22 Inhibits Epithelial Stem Cell Expansion in an Ileal Organoid Model

doi: 10.1016/j.jcmgh.2018.06.008

Figure Lengend Snippet: Il22ra1 is expressed heterogeneously throughout the crypt. ( A ) The Il22ra1 gene expression profile characterized in FACS-isolated total epithelium (CD326+), absorptive/goblet differentiated cells (Sox9-EGFP neg ), TA progenitor cells (Sox9-EGFP sublow ), ISCs (Sox9-EGFP low ), enteroendocrine/tuft cells (Sox9-EGFP high ), and Paneth cells (Sox9-EGFP high , CD24 high ). Technical replicate n = 3; biological N = 3 mice. Significance was calculated by 1-way analysis of variance with Tukey multiple comparisons; bars that are not connected by the same letter are statistically significant ( P < .05). ( B ) Left : t-SNE analysis of single-cell RNA sequence analysis of mouse small intestinal epithelium. Each color represents a different population defined in the original analysis based on lineage-specific transcriptomic signatures. Right : Table depicts the number of cells in each lineage category expressing IL22ra1. ( C ) Cells from the t-SNE profiles in the graph in panel B are highlighted specifically for the expression of IL22ra1 levels in all epithelial cells. Darker shades of grey represent higher expression levels. Pink circles represent no expression. ( D ) The same analysis in panel C except only ISCs are shown. ( E ) The same analysis in panel C except only TA progenitors are shown. ( F ) Representative immunohistochemistry of IL22RA1 (red) and cell nuclei (blue) in a mouse ileal crypt. ( G ) FACS analysis of fixed cell populations described in panel A stained for IL22RA1. Technical replicate n = 3; biological N = 3 mice. Bars represent parts of whole. EC, enterocyte; EE, enteroendocrine; EEC, enteroendocrine; Max, maximum; Min, minimum.

Article Snippet: Primary antibodies and dilutions used were as follows: KI67 (rabbit, 1:100, M7249; Dako), LYZ (goat, 1:500, sc-12091; Santa Cruz, Dallas, TX), CD326 epithelial cell adhesion molecule (EPCAM)/CD326 (rat, 1:500, H8201, clone G8.8; Biolegend, San Diego, CA), IL22RA1 (rat, 1:50, FAB42941P; R&D Systems), OLFM4 (rabbit, 1:250, 39141; Cell Signaling Technology).

Techniques: Expressing, Isolation, Sequencing, Immunohistochemistry, Staining